The PGA Tour stays in Florida this week for 'golf's fifth major' with the 2022 Players Championship set to tee off on Thursday, March 10 at TPC Sawgrass in Ponte Vedra Beach, Fla.. The Players is annually one of the most anticipated tournaments on the PGA Tour calendar, and features several iconic holes. The Players Championship field is absolutely loaded with 48 of the top 50 golfers in the world set to participate. The 2022 Players Championship purse is $20 million, with $3.6 million going to the winner. Justin Thomas, Collin Morikawa, and Jon Rahm are the 14-1 betting favorites in the latest Players Championship odds from Caesars Sportsbook. Other top contenders at TPC Sawgrass include Rory McIlroy (18-1), Viktor Hovland (20-1), Scottie Scheffler (25-1), and Patrick Cantlay (25-1). All will likely be popular One and Done picks this week at the Players Championship.

Before locking in your own 2022 Players Championship one and done picks, you NEED to see what Daily Fantasy Sports pro Mike McClure has to say.

The One and Done format is growing in popularity. It has several noticeable similarities to NFL Survivor pools, with the main difference being entries are not eliminated with a bad week. Players pick one golfer per week and earn points based on their selected golfer's prize money for that tournament. Golfers can only be used once per season, and the point format makes nailing majors and big money tournaments critical.

McClure is a DFS legend with nearly $2 million in career winnings, and he's been RED-HOT on his PGA picks dating back to the PGA Tour restart in June of 2020. McClure uses his proprietary simulation model to analyze the field and crush his golf picks.

Last week at the Arnold Palmer Invitational, McClure listed Tyrell Hatton and Matt Fitzpatrick among his top one and done options. Both finished in the top-10, with Hatton finishing T-2 ($908,000) and Fitzpatrick finishing T-9 ($339,000).

Earlier this year at the Waste Management Phoenix Open, McClure's top three One and Done picks were Xander Schauffele, Brooks Koepka, and Louis Oosthuizen. Schauffele and Koepka finished T-3, one stroke behind the leaders, which was good for $434,600 each. Oosthuizen finished T-14, and won $133,250.

At the AT&T Pebble Beach Pro-Am, McClure was all over Matthew Fitzpatrick. The 27-year-old went out and shot 14-under par for the tournament, finishing in a tie for sixth place, taking home $293,625.

At the Farmers Insurance Open, McClure's top pick was 25-year-old Will Zalatoris. The result: Zalatoris finished in sole possession of second place, taking home $915,600. While he came up short against eventual winner Luke List in a one-hole playoff, Zalatoris' performance at Torrey Pines was HUGE for one and done players.

At The American Express, McClure was all over Patrick Cantlay and Sungjae Im, who finished 9th ($222,300) and T-11 ($184,300), respectively. 

At the Sony Open 2022, McClure's model listed Hideki Matsuyama among the top contenders. The reigning Masters champion went out and overcame a five-stroke deficit on the back nine of the final round to notch his eighth career PGA Tour victory.

At the 2022 Sentry Tournament of Champions, McClure included Jon Rahm and Daniel Berger among his top PGA picks. The result: Rahm came in second with a score of 33-under par, while Berger secured a top-five finish with a score of 25-under par. Anybody that included them in their one and done picks is in great shape. 

At the 2021 World Wide Technology Championship at Mayakoba in November, the model was all over Viktor Hovland (18-1) winning his third PGA Tour title. At the 2021 Open Championship, McClure's best bets included Collin Morikawa winning outright even though he was listed as a massive 40-1 long shot. In addition, McClure's model was all over Jon Rahm's (10-1) first career major championship victory at the 2021 U.S. Open. 

McClure's model is up nearly $10,000 on its best bets since the restart, nailing tournament after tournament. Anyone who has followed it has seen MASSIVE returns, and anyone tailing his one and done picks should be in great shape. 

Now, McClure has set his sights on the 2022 Players Championship and just revealed his optimal One and Done picks. They are a must-see for any player looking for an edge in their One and Done pool.

We can tell you that one of McClure's favorite Players Championship Open One and Done picks is Justin Thomas, who is currently listed at 14-1 to win the tournament at Caesars. Thomas, currently No. 8 in the Official World Golf Rankings, is the defending Players champion, and is a threat to win every tournament he enters. The 28-year-old has three top-10's in four starts in 2022, and finished in sixth place in his most recent outing at the Genesis Invitational. With the massive amount of talent in the Players Championship field, McClure thinks Thomas could fly under the radar this week, making him an excellent one and done pick at TPC Sawgrass.

McClure is also targeting another One and Done sleeper who's listed at 50-1 in the 2022 Players Championship odds and is primed to blow up this week, giving you a HUGE return! Picks like these could be the difference between winning your One and Done pool or going home with nothing. You ABSOLUTELY need to see who it is before locking in your pick.

So what are the top One and Done picks for the 2022 Players Championship? And which under-the-radar golfers offer HUGE One and Done value? ... Join SportsLine here to see the top 2022 Players Championship One and Done picks, all from the expert who's made nearly $2 million in daily Fantasy sports!