A 14-game slate on Sunday means there will be plenty of NFL prop bets to ponder. Before locking in any 2022 NFL prop picks for Week 1, be sure to see the top NFL picks and predictions from NFL props expert Alex Selesnick.

Selesnick (aka PropStarz) specializes in NFL, MLB and NBA prop betting, where he implements a combination of research, statistical analysis and mathematical modeling. His background playing competitive fantasy sports, poker, Scrabble and backgammon helped form the foundation of his sports betting approach.

The expert was an impressive 53-37 on his picks during the 2021 NFL regular season for SportsLine and is 58-31 (+20.66 units) on MLB prop plays this year. He's also up nearly 235 units on NBA props and futures plays over the past two-plus seasons.

After poring over scores of available NFL prop odds, PropStarz found three picks he loves, including Kansas City's JuJu Smith-Schuster going Over 46.5 receiving yards in his debut with the Chiefs. The 25-year-old wide receiver racked up over 1,400 yards with Pittsburgh in 2018 and is expected to be one of Patrick Mahomes' top targets now that Tyreek Hill is in Miami.

PropStarz also has locked down two other CONFIDENT prop bets, including calling for a running back to go Over his projected rushing attempts against a weak defense. You NEED to see what they are before deciding in your bets.

What NFL prop bets should you make on opening weekend? And which running back is a MUST-BACK? ... Join SportsLine right now to see the top NFL prop picks you can make, all from the expert who went 53-37 on his NFL prop bets last season!