On Friday night, the Carolina Panthers and the New England Patriots will square off in the second week of the preseason. New England went 10-7 in 2021 and notched another postseason berth. Carolina's season wasn't a success after they finished last in the NFC South with a record of 5-12. Kickoff at Gillette Stadium in Foxborough MA is set for 7 p.m. ET. Carolina is a 2-point favorite in the latest Panthers vs. Patriots odds from Caesars Sportsbook, while the over/under for total points scored is 40.5. 

Before you make any Panthers vs. Patriots picks of your own, you NEED to hear what NFL expert Larry Hartstein has to say.

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A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed while working for Pro Football Focus. Entering the 2022 NFL season, he is 427-344 all-time on NFL sides (plus $3,764 for $100 players), including 394-330 against the spread. Hartstein went 68-50 ATS (58 percent) and 8-3 on money-line plays last season for a profit of $1,552. 

Hartstein has also nailed nine of his last 11 picks involving the Panthers, returning almost $700 for $100 players. Anybody who has been following him is WAY UP.

Now, Hartstein has locked in another confident pick against the spread pick for Panthers vs. Patriots. We can tell you he's leaning Under the total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

So who wins Panthers vs. Patriots? And what critical X-factor makes one side of the spread hit HARD? Join SportsLine now to find out, all from the expert on a 9-2 run on Carolina picks! Use promo code FB30 to get half-off your first year of picks AND a FREE YEAR if any team scores 30 points this week!

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