The Murray State Racers will take on the San Francisco Dons at 9:40 p.m. ET on Thursday at Gainbridge Fieldhouse in a first-round matchup in the 2022 NCAA Tournament. San Francisco is 24-9 on the season and earned a No. 10 seed in the East Region while the Racers are 30-2 and are the No. 7 seed. 

The Racers are favored by two points in the latest Murray State vs. San Francisco odds from Caesars Sportsbook, and the over-under is set at 137. Before making any San Francisco vs. Murray State picks or predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,500 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Murray State vs. San Francisco 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 80 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Murray State vs. San Francisco? And which side of the spread hits well over 80 percent of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.