The Miami Hurricanes and USC Trojans face off in a first-round matchup of the 2022 NCAA Tournament at 3:10 p.m. ET on Friday. USC is favored by 2.5 points at Caesars Sportsbook, while the Over-Under is set at 139.5 (see up-to-date odds for every game this week on our college basketball odds page). 

Before making any Miami vs. USC picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,500 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Miami is strong on offense, led by veteran guards. The Hurricanes are in the top 20 nationally in offensive efficiency, finishing behind only Duke in the ACC. Miami is elite in ball security, committing a turnover on only 14.2 percent of offensive possessions. The Hurricanes are also in the top 30 of the nation in shooting efficiency, making 54.8 percent of 2-point attempts, 35.3 percent of 3-point attempts and 74.3 percent of free-throw attempts this season.

The model also knows USC is in the top 50 nationally in both offense and defense. The Trojans finished in the top three in the Pac-12 in offensive efficiency, leading the conference with a 35.3 percent offensive rebound rate. USC is also shooting 35.4 percent from 3-point range with above-average free-throw creation.

Now, it has set its sights on Miami vs. USC. We can tell you the model is leaning over the total, and it also says one side of the spread hits in over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Miami vs. USC? And which side of the spread hits in over 50 percent of simulations? ... Join SportsLine right now to find out which side of the Miami vs. USC spread you should be all over Friday, all from the model on a roll on college basketball picks!