The 2022 MLB divisional round begins on Tuesday with four Division Series Game 1s, including the Los Angeles Dodgers hosting the rival San Diego Padres at Dodger Stadium in Los Angeles. The Dodgers (111-51) are rested after finishing the regular season with the best record in baseball. Meanwhile the Padres are coming off a Wild Card Series victory over the Mets, capped by a 6-0 victory in Game 3 on Sunday. 

Los Angeles is a -235 favorite in the latest Dodgers vs. Padres odds from Caesars Sportsbook, while San Diego is a +192 underdog. The over/under for runs scored is 7. In other Game 1s on Tuesday, the Braves host the Phillies, the Astros take on the Mariners in Houston and the Yankees and Guardians collide in the Bronx. (See up-to-date lines for every game on our MLB odds page.)

Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it enters the divisional round on a 20-11 roll on top-rated MLB money-line picks, returning more than $600. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win the World Series. Anybody who has followed the model has seen huge returns.

Now, the model has set its sights on the MLB Division Series schedule for Tuesday, Oct. 11, and has generated a four-leg parlay that would pay well over 16-1! The parlay starts at 1:07 p.m. ET, so you still have time to make your MLB picks.

We can tell you that one of the picks is the Guardians (-130) to cover the +1.5 run line against the Yankees. But the model has three other picks, including one on a big money line underdog! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

So what big money line underdog is a MUST-BACK? And what other wagers do you need to include in your parlay for a payout of well over 16-1? ... Join SportsLine right now to find out which picks you should be all over on Tuesday, all from the model that is on a 20-11 run on top-rated money-line picks!