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    2022 MLB Division Series odds, lines, picks: Advanced computer model includes the Padres in parlay for Oct. 15 that would pay well over 5-1

    The SportsLine Projection Model has identified a four-leg parlay for Saturday's Division Series games that would pay well over 5-1

    The Cleveland Guardians look to take control of their American League Division Series on Saturday when they take on the New York Yankees in Game 3 of their series at Progressive Field in Cleveland. After losing Game 1, the Guardians rallied from an early 2-0 deficit on Friday to force extra innings where they outlasted the Yankees 4-2 in 10. The win evened the series and gave Cleveland home field advantage.

    New York is a -120 favorite in the latest Yankees vs. Guardians odds from Caesars Sportsbook, while Cleveland is a +100 underdog. The over/under for runs scored is 6.5. In other games on Saturday, the Phillies host the Braves, the Astros take on the Mariners in Seattle and the Dodgers battle the Padres in San Diego. (See up-to-date lines for every game on our MLB odds page.)

    Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

    The SportsLine Projection Model simulates every MLB game 10,000 times, and it entered the divisional round on a 20-11 roll on top-rated MLB money-line picks, returning more than $600. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win the World Series. Anybody who has followed the model has seen huge returns.

    Now, the model has set its sights on the MLB Division Series schedule for Saturday, Oct. 15, and has generated a four-leg parlay that would pay well over 5-1! The parlay starts at 2:07 p.m. ET, so you still have time to make your MLB picks.

    We can tell you that one of the picks is the Padres (-170) to cover the +1.5 run line against the Dodgers. But the model has three other picks, including one selection than hits more than 70% of the time! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

    So which MLB teams should you back on Saturday? And what other wagers do you need to include in your parlay for a payout of well over 5-1? ... Join SportsLine right now to find out which picks you should be all over on Saturday, all from the model that is on a 20-11 run on top-rated money-line picks!

    GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!

    JOIN NOW
    SportsLine Staff
    SportsLine Staff

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