A spot in the final is on the line in the latest version of El Clasico when Barcelona host Real Madrid in a 2022-23 Copa del Rey semifinal second-leg match Wednesday at Camp Nou. This will be the fifth meeting between the teams this season, including a 1-0 Barcelona victory in the first leg March 2 at Bernabeu Stadium. The hosts also lead the Spanish La Liga by 12 points over second-place Real Madrid, the reigning league and European champions.

Kickoff is set for 3 p.m. ET in Barcelona, Spain. Caesars Sportsbook lists Barcelona as +135 favorites (risk $100 to win $135) on the 90-minute moneyline in its latest Barcelona vs Real Madrid odds, while Real Madrid are +185 underdogs. A draw is priced at +230 and the over/under for total goals is 2.5. Barcelona are -450 to qualify for the final, with Real Madrid priced at +300. (For more soccer coverage, click here)

Before you make any Barcelona vs. Real Madrid picks or any other Spanish Copa del Rey predictions, you MUST see what SportsLine soccer insider Martin Green has to say! 

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Green is 67-73-1 (+3.02 units) on his SportsLine soccer picks in 2023, and he is 42-46 in his predictions on England's league and domestic cup competitions.

Green knows Barca have tons of confidence with a 1-0 aggregate lead and playing at home. They also beat Los Blancos 2-1 in a league El Clasico matchup March 19 and come in off a 4-0 victory against Elche on Sunday. Barca are 11-2-0 with a 27-2 goal advantage at Camp Nou in league play. Robert Lewandowski has 27 goals in 34 matches in all competitions, and fellow new addition Raphinha has nine goals and eight assists.

The expert also has considered that Los Blancos come in off a 6-0 thrashing of Valladolid in a league match Sunday, with star striker Karim Benzema netting a hat trick. Benzema has 21 goals in 29 matches in all competitions, while Vinicius Junior has 16 goals and 11 assists in 40 games. Real's only two losses over their past 10 matches are to Barcelona, so the 35-time La Liga champions will be fired up to break through again.

Green has taken an in-depth look at the Barcelona vs. Real Madrid match from every angle, and we can tell you he is taking Over on the goal total. He has two other CONFIDENT best bets, including a play on one side to win, and his full breakdown of the match. You ABSOLUTELY need to see his picks and analysis before making any selections of your own. 

So, who wins Wednesday's Real Madrid vs. Barcelona Copa del Rey semifinal matchup? And where does all the betting value lie for the El Clasico match? ... Join SportsLine now to see Martin Green's best bets for Barcelona vs. Real Madrid, all from the soccer insider who knows the sport inside and out!