Royals vs. Guardians odds, line, start time, picks, best bets for April 11 matchup from proven model
SportsLine's projection model, which is on a 34-19 roll on top-rated run-line picks, has locked in its MLB picks for the Kansas City Royals vs. Cleveland Guardians on Friday
The Cleveland Guardians (6-6) host the Kansas City Royals (7-6) in an AL Central matchup on Friday. The Guardians topped the Chicago White Sox 6-1 to complete the three-game sweep on Thursday. On the other side, the Royals beat the Minnesota Twins 3-2 in their last outing.
First pitch is scheduled for 6:10 p.m. ET at Progressive Field in Cleveland, Ohio. The Guardians are the -125 money-line favorites (bet $125 to win $100) in the latest Royals vs. Guardians odds, while the Royals are +106 underdogs (bet $100 to win $106). The over/under for total runs scored is 7 in the latest MLB odds via SportsLine consensus.
Before you make any Royals vs. Guardians picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 3 of the 2025 MLB season on a 34-19 roll on top-rated run-line MLB betting picks (+629). Anybody following at sportsbooks and on betting apps could have seen STRONG returns!
The model has simulated Royals vs. Guardians 10,000 times and the results are in. We can tell you the model is going Over on the run total, and it also says one side of the money line has ALL the value!
Who wins Royals vs. Guardians, and which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model on a 34-19 roll on top-rated MLB run-line picks!