The No. 9 Penn State Nittany Lions will face their first ranked opponent of the season when they host the No. 19 Illinois Fighting Illini on Saturday night. Penn State is coming off a 56-0 win over Kent State and is playing the third game of a four-game homestand. Illinois has already knocked off two ranked teams this season, including then-No. 22 Nebraska in overtime last week. 

Kickoff is set for 7:30 p.m. ET on Saturday at Beaver Stadium. Penn State is favored by 17.5 points in the latest Penn State vs. Illinois odds, while the over/under is 47.5 points, per SportsLine consensus. Before entering any Illinois vs. Penn State picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks. Anyone who has followed it has seen strong returns.

The model has simulated Penn State vs. Illinois 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Penn State vs. Illinois? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.