MLB odds, lines, picks: Advanced computer model includes the White Sox in parlay for Friday, Sept. 22 that would pay almost 12-1
The SportsLine Projection Model, which is 84-66 on all top-rated MLB picks this season, has identified a three-leg parlay for Friday that would pay almost 12-1
The Minnesota Twins can clinch the AL Central on Friday when they host the Los Angeles Angels at Target Field in Minneapolis. The Twins (81-72) lead the division by 8.5 games over the Guardians and nine games over the Tigers. Minnesota would clinch the division with either a win over the Angels or losses by both Cleveland and Detroit on Friday.
Minnesota is a -266 favorite (risk $266 to win $100) in the latest Twins vs. Angels odds, while Los Angeles is a +217 underdog. The over/under for runs scored is 8. The game is one of 15 on the MLB schedule for Friday. (See up-to-date lines for every game on our MLB odds page.)
Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons. It entered the penultimate full week of the 2023 MLB season 84-66 on all top-rated MLB picks this season and has excelled on top-rated run-line picks, going 15-5 (+653). Anybody following has seen big returns.
Now, the model has set its sights on the MLB schedule for Friday and has generated a three-leg parlay that would pay almost 12-1. The parlay doesn't start until 7:10 p.m. ET, giving you plenty of time to make your MLB picks.
We can tell you that one of the picks is the White Sox (+180) to beat the Red Sox. But the model has two other picks, including a play on an even bigger AL underdog. You ABSOLUTELY need to see them before locking in any MLB picks of your own.
So which big AL underdog is a MUST-BACK? And what other teams do you need to include in your parlay for a payout of almost 12-1? ... Join SportsLine right now to find out which picks you should be all over on Friday, all from the model that is 84-66 on all top-rated MLB picks this season.