The top-seeded Gonzaga Bulldogs will put their 30-0 record on the line when they take on the red-hot 11th-seeded UCLA Bruins in a 2021 NCAA Tournament Final Four semifinal matchup on Saturday. Tip-off from Lucas Oil Stadium in Indianapolis is set for 8:34 p.m. ET on CBS. 

The Bulldogs are favored by 14 points in the latest UCLA vs. Gonzaga odds from William Hill Sportsbook while the Over-Under for total points scored is 146.5 (Check out the current Final Four odds on the SportsLine college basketball odds page.).

Before you lock in your Final Four picks or UCLA vs. Gonzaga predictions, you have to see what SportsLine senior analyst Larry Hartstein has to say. 

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach. In his last 381 college basketball picks, he is 216-165 against the spread, returning $3,413 to $100 players. And he enters the third week of the NCAA Tournament on a major heater, going 21-9 with his last 30 college basketball picks (encompassing the NCAA Tournament, NIT and College Basketball Invitational). Anybody who has been following him is WAY UP!

Now, with the Bruins and Bulldogs colliding in a NCAA Tournament semifinal game, Hartstein has released another against-the-spread pick. We can tell you that he is leaning Under the total, but his much stronger play is on the spread. In fact, he has identified a crucial X-factor that has him going BIG on one side! You ABSOLUTELY need to see it before locking in your own picks.

Who wins UCLA vs. Gonzaga in the Final Four? And what crucial X-factor makes one side of the spread a MUST-BACK? ... Join SportsLine right now to see which side of the UCLA vs. Gonzaga spread you need to back, all from the expert who's on a 21-9 run on picks involving college basketball!