NFL Week 3 schedule 2021: Odds, expert picks, predictions, best bets, TV coverage for full slate of games

Odds, picks, best bets, and TV coverage for every game on the 2021 NFL Week 3 schedule

SportsLine Staff

Through two weeks, the 2021 NFL season has not disappointed. Week 1 was full of upsets and games decided in the final minutes. In Week 2, Patrick Mahomes's Chiefs and Lamar Jackson's Ravens delivered an instant classic on Sunday Night Football; the Seattle Seahawks and Tennessee Titans went to overtime; and two more games, the Cardinals vs. Vikings and Cowboys vs. Chargers, were decided by field goals in the final seconds.

With the Green Bay Packers blowout win over the Detroit Lions on Monday Night Football, against the spread underdogs notched a slight 9-7 advantage over the favorites in Week 2, which was a big shift from Week 1 when the underdogs posted a 12-4 record. Will Week 3 be the week where the betting favorites prevail? Or will it be all about the ATS underdogs again?

The NFL Week 3 schedule features another full slate of games with several intriguing matchups including Chiefs vs. Chargers, where Justin Herbert will face off with Patrick Mahomes; the Buccaneers vs. Rams, in a matchup between arguably the top two teams in the NFC; and Cowboys vs. Eagles on Monday Night Football, where fans will get another taste of one of the nastiest rivalries in the NFL.

Here is a full rundown of the NFL Week 3 slate of games and TV schedule, as well as odds, picks, and predictions for several matchups.

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Carolina Panthers vs. Houston Texans

Panthers vs. Texans date and time: Thursday, September 23 at 8:20 p.m. ET
Panthers vs. Texans spread: Panthers -7.5
Panthers vs. Texans over-under: 43.5
Panthers vs. Texans moneyline: Panthers -380, Texans +300
Panthers vs. Texans TV Coverage: NFL Network

Expert Panthers vs. Texans picks HERE.

Washington Football Team vs. Buffalo Bills

Bills vs. Washington date and time: Sunday, September 26 at 1 p.m. ET
Bills vs. Washington spread: Bills -9
Bills vs. Washington over-under: 45.5
Bills vs. Washington moneyline: Bills -420, Washington +320
Bills vs. Washington TV coverage: Fox

Chicago Bears vs. Cleveland Browns

Bears vs. Browns date and time: Sunday, September 26 at 1 p.m. ET
Bears vs. Browns spread: Browns -7
Bears vs. Browns over-under: 46.5
Bears vs. Browns moneyline: Browns -330, Texans +260
Bears vs. Browns TV coverage: Fox

Expert Bears vs. Browns picks HERE.

Baltimore Ravens vs. Detroit Lions

Ravens vs. Lions date and time: Sunday, September 26 at 1 p.m. ET
Ravens vs. Lions spread: Ravens -8.5
Ravens vs. Lions over-under: 49.5
Ravens vs. Lions moneyline: Ravens -420, Lions +320
Ravens vs. Lions TV coverage: CBS

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Indianapolis Colts vs. Tennessee Titans

Colts vs. Titans date and time: Sunday, September 26 at 1 p.m. ET
Colts vs. Titans spread: Titans -5
Colts vs. Titans over-under: 48
Colts vs. Titans moneyline: Titans -260, Colts +210
Colts vs. Titans TV coverage: CBS

Los Angeles Chargers vs. Kansas City Chiefs

Chiefs vs. Chargers date and time: Sunday, September 26 at 1 p.m. ET
Chiefs vs. Chargers spread: Chiefs -6.5
Chiefs vs. Chargers over-under: 55.5
Chiefs vs. Chargers moneyline: Chiefs -250, Chargers +205
Chiefs vs. Chargers TV coverage: CBS

New Orleans Saints vs. New England Patriots

Saints vs. Patriots date and time: Sunday, September 26 at 1 p.m. ET
Saints vs. Patriots spread: Patriots -3
Saints vs. Patriots over-under: 41.5
Saints vs. Patriots moneyline: Patriots -160, Saints +140
Saints vs. Patriots TV coverage: Fox

Atlanta Falcons vs. New York Giants

Giants vs. Falcons date and time: Sunday, September 26 at 1 p.m. ET
Giants vs. Falcons spread: Giants -3
Giants vs. Falcons over-under: 48
Giants vs. Falcons moneyline: Falcons +140, Giants -160
Giants vs. Falcons TV coverage: Fox

Cincinnati Bengals vs. Pittsburgh Steelers

Steelers vs. Bengals date and time: Sunday, September 26 at 1 p.m. ET
Steelers vs. Bengals spread: Steelers -4
Steelers vs. Bengals over-under: 44
Steelers vs. Bengals moneyline: Steelers -200, Bengals +170
Steelers vs. Bengals TV coverage: CBS

Arizona Cardinals vs. Jacksonville Jaguars

Cardinals vs. Jaguars date and time: Sunday, September 26 at 1 p.m. ET
Cardinals vs. Jaguars spread: Cardinals -7.5
Cardinals vs. Jaguars over-under: 52
Cardinals vs. Jaguars moneyline: Cardinals -360, Jaguars +285
Cardinals vs. Jaguars TV coverage: Fox

Expert Cardinals vs. Jaguars picks HERE.

New York Jets vs. Denver Broncos

Broncos vs. Jets date and time: Sunday, September 26 at 2:05 p.m. ET
Broncos vs. Jets spread: Jets -10.5
Broncos vs. Jets over-under: 41
Broncos vs. Jets moneyline: Broncos -650, Jets +450
Broncos vs. Jets TV coverage: CBS

Miami Dolphins vs. Las Vegas Raiders

Raiders vs. Dolphins date and time: Sunday, September 26 at 2:05 p.m. ET
Raiders vs. Dolphins spread: Raiders -3.5
Raiders vs. Dolphins over-under: 45
Raiders vs. Dolphins moneyline: Dolphins +155, Raiders -180
Raiders vs. Dolphins TV coverage: CBS

Tampa Bay Buccaneers vs. Los Angeles Rams

Buccaneers vs. Rams date and time: Sunday, September 26 at 4:25 p.m. ET
Buccaneers vs. Rams spread: Buccaneers -1
Buccaneers vs. Rams over-under: 55.5
Buccaneers vs. Rams moneyline: Rams +100, Buccaneers -120
Buccaneers vs. Rams TV coverage: Fox

Seattle Seahawks vs. Minnesota Vikings

Vikings vs. Seahawks date and time: Sunday, September 26 at 4:25 p.m. ET
Vikings vs. Seahawks spread: Seahawks -2
Vikings vs. Seahawks over-under: 55
Vikings vs. Seahawks moneyline: Vikings -125, Seahawks +105
Vikings vs. Seahawks TV coverage: Fox

Green Bay Packers vs. San Francisco 49ers

Packers vs. 49ers date and time: Sunday, September 26 at 8:20 p.m. ET
Packers vs. 49ers spread: 49ers -3.5
Packers vs. 49ers over-under: 49.5
Packers vs. 49ers moneyline: Packers +160, 49ers -190
Packers vs. 49ers TV coverage: NBC

Philadelphia Eagles vs. Dallas Cowboys

Cowboys vs. Eagles date and time: Monday, September 20 at 8:15 p.m. ET
Cowboys vs. Eagles spread: Cowboys -4
Cowboys vs. Eagles over-under: 52
Cowboys vs. Eagles moneyline: Cowboys -210, Eagles +175
Cowboys vs. Eagles TV coverage: ESPN

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