A spot in the AFC Playoffs is on the line when Justin Herbert and the Los Angeles Chargers travel to Lucas Oil Stadium to take on Nick Foles and the Indianapolis Colts on Monday Night Football. With a win the Chargers will clinch one of the AFC's three Wild Card spots with two full weeks still to play. Los Angeles is a 3.5-point favorite and the over/under is set at 44.5 points in the latest Colts vs. Chargers odds from Caesars Sportsbook. In addition to the Chargers vs Colts point spread and Week 16 NFL betting lines, Caesars is also offering a plethora of prop bet options for this matchup on Monday Night Football, and SportsLine NFL expert Jimmie Kaylor has just revealed his top plays.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who has been cashing big all season, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

Kaylor has been spot-on all season, hitting on epic NFL DFS and Prop picks like Jerry Jeudy (4-102-1), Stefon Diggs (12-148-3, 6-106-1, 7-92-1), Amari Cooper (7-101-1, 5-131-1), Nick Chubb (23-113-1, 23-101-2), CeeDee Lamb (8-87-1), Deebo Samuel (6-115-1) Cooper Kupp (14-122), Travis Kelce (7-25-4, 10-106), Davante Adams (3-124-2), Justin Fields (179-1-1, 82-1), Derrick Henry (132-2), Jimmy Garoppolo (228-4), Michael Pittman (7-61-1), Christian McCaffrey (26-108-1, 6-30), Kirk Cousins (460-4), Justin Jefferson (12-123-1), J.K. Dobbins (13-125), and T.J. Hockenson (13-109-2). Anyone who has followed his picks is WAY UP!

Now, Kaylor has locked in on Chargers vs. Colts and just revealed his top XXX prop bet picks for this Week 16 NFL Monday Night Football matchup.

We can tell you that one of Kaylor's favorite prop bet picks for Indianapolis vs. Los Angeles on Monday Night Football is Chargers all-purpose running back Austin Ekeler to go over 4.5 receptions at -151 (risk $151 to win $100) odds. Ekeler has 95 receptions on the season, sixth most in the league, and the Colts have had issues defending running backs out of the backfield in the passing game.

In addition to his other picks, Kaylor also has another prop bet pick offering a plus-money payout that he fully expects to cash on Monday night. You ABSOLUTELY need to see before locking in any prop bet picks of your own for MNF.

What are Kaylor's other top NFL prop bet picks for Falcons vs. Panthers on Thursday Night Football? And which star wide receiver goes WAY OVER his receiving yards total? Join SportsLine now to see NFL expert Jimmie Kaylor's top player prop bet picks for TNF, all from the red-hot NFL expert who has been cashing in BIG all season!