Broncos vs. Jaguars NFL Week 2 injury report, odds, spread: Jerry Jeudy, Ronald Darby out; Trevor Lawrence now favored to lead league in interceptions

The Denver Broncos will be without starting receiver Jerry Jeudy and cornerback Ronald Darby and could be without stud pass-rushing linebacker Bradley Chubb when they visit the Jacksonville Jaguars on Sunday. The Jags are on a 16-game losing streak – only two other teams have reached 20 losses in a row. Off an uneven NFL debut, Jacksonville QB Trevor Lawrence is no longer the Offensive Rookie of the Year favorite and is the +700 leader to lead the NFL in picks.

The Chicago Cardinals of 1942-45 lost 29 in a row for the overall mark, and the Super Bowl-era longest skid belong to Tampa Bay Buccaneers of 1976-77 at 26 straight, so Jacksonville has a long way to go to catch those clubs. Currently, the Jaguars are in a five-way tie for the 12th-longest losing streak in league history.

Remember, they were 3-point favorites last week in Houston but were crushed 37-21. Lawrence certainly showed some positive signs in throwing for 332 yards and three touchdowns but also was picked three times – he never threw three interceptions in a game at Clemson and had never previously had a losing record as a starting QB dating to his high school days in Georgia.

Lawrence is now a +550 second-favorite behind New England's Mac Jones (+400) to win Offensive Rookie of the Year and a +700 leader to top the NFL in interceptions. The only other QBs to throw at least two in Week 1 were future Hall of Famers Tom Brady and Aaron Rodgers. Lawrence is given an Over/Under season total of 18.5 picks.

It appears Jacksonville got out of Week 1 without any major injuries, but that wasn't the case for Denver in its 27-13 win at the Giants as both Jeudy (high-ankle sprain) and Darby (hamstring) have landed on injured reserve, meaning they will each miss a minimum of three games. Tim Patrick should take most of Jeudy's snaps and was a popular Fantasy pickup this week after he had four catches for 39 yards and a TD vs. the Giants.

First-round rookie Patrick Surtain will take over for Darby, who played all 61 defensive snaps and finished tied with a team-high six tackles vs. the Giants. Chubb didn't play in the opener because of an ankle injury and the former No. 5 overall pick is questionable for Jacksonville.

Denver is currently a 6-point favorite Sunday and it's another chance for bettors to cash in on Broncos QB Teddy Bridgewater. He is now 22-3 ATS in career on the road, the best such cover mark in league history. Teddy could have a big day considering Jacksonville has allowed at least 24 points in 16 straight games, an NFL record. 

Via SportsLine oddsmakers: Many many interceptions will Trevor Lawrence throw this season?

• Over 18.5 -110
• Under 18.5 -110

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