| Thursday, Dec. 20, 2007 | |||
| Pittsburgh Steelers at St. Louis Rams | |||
 27 | Steelers QB Ben Roethlisberger will test a Rams defense that intercepted Brett Favre twice, but also allowed two passing touchdowns. Rams RB Steven Jackson could have success against a Steelers defense that was gashed by Jacksonville for 224 rushing yards. Result: Pittsburgh Steelers 41, St. Louis Rams 24 | ||
 17 | |||
| Saturday, Dec. 22, 2007 | |||
| Dallas Cowboys at Carolina Panthers | |||
 31 | Cowboys QB Tony Romo completed a season-low 13 of 36 passes last week. Romo could struggle against a Panthers defense that shut down the Seahawks until they resorted to a prevent pass defense on the game's final series. Panthers RB DeAngelo Williams could struggle against a Cowboys defense that held Brian Westbrook in check for most of the game. Result: Dallas Cowboys 20, Carolina Panthers 13 | ||
 17 | |||
| Sunday, Dec. 23, 2007 | |||
| Cleveland Browns at Cincinnati Bengals | |||
 24 | Last week, the Browns threw for 137 yards in blinding, swirling wind and snow. QB Derek Anderson should have more success this week against a Bengals defense that allowed third-string 49ers QB Shaun Hill to complete 21 out of 28 passes for a 105.8 passer rating. The Bengals' rushing offense will test a Browns defense that finally held a back under 100 yards. Result: Cleveland Browns 14, Cincinnati Bengals 19 | ||
 22 | |||
| Green Bay Packers at Chicago Bears | |||
 24 | Last week, the Packers were held to 52 rushing yards. Packers RB Ryan Grant will test a Bears defense that limited Adrian Peterson to 78 yards on 20 carries, but he still scored twice. Bears QB Kyle Orton could struggle against a Packers defense that blitzed a lot last week and sacked Marc Bulger four times. Result: Green Bay Packers 7, Chicago Bears 35 | ||
 17 | |||
| NY Giants Giants at Buffalo Bills | |||
 17 | Giants RB Brandon Jacobs rushed for 130 yards last week and should have similar success against a Bills defense that was gouged for 163 yards on 33 carries. Bills RB Marshawn Lynch should have success against a Giants defense that gave up 153 rushing yards to the Redskins. Result: Buffalo Bills 21, NY Giants Giants 38 | ||
 16 | |||
| Philadelphia Eagles at New Orleans Saints | |||
 23 | Saints QB Drew Brees could struggle against an Eagles defense that intercepted Tony Romo three times. Eagles RB Brian Westbrook could find running room against a Saints defense that gave up 103 yards on 22 carries. Result: New Orleans Saints 23, Philadelphia Eagles 38 | ||
 21 | |||
| Houston Texans at Indianapolis Colts | |||
 28 | Colts QB Peyton Manning passed for 276 yards with one touchdown and an interception. Manning could struggle against a Texans defense that put a lot of pressure on Jay Cutler, who was sacked five times. Texans QB Sage Rosenfels could struggle against a Colts defense that limited Josh McCown to 94 passing yards. Result: Indianapolis Colts 38, Houston Texans 15 | ||
 19 | |||
| Oakland Raiders at Jacksonville Jaguars | |||
 28 | Last week, the Jaguars pounded the Steelers for 224 rushing yards. RB Fred Taylor could struggle against a Raiders defense that surrendered just 58 rushing yards on 20 carries against the Colts. Raiders RB Justin Fargas could have success against a Jaguars defense that allowed 100 rushing yards. Result: Jacksonville Jaguars 49, Oakland Raiders 11 | ||
 13 | |||
| Kansas City Chiefs at Detroit Lions | |||
 26 | Lions QB Jon Kitna tied his career high with five interceptions last week, but should have more success against a Chiefs defense that allowed Vince Young to earn a 109 passer rating with two passing touchdowns. Chiefs RB Kolby Smith should have success against a Lions defense that allowed 274 rushing yards. Result: Detroit Lions 25, Kansas City Chiefs 20 | ||
 20 | |||
| Atlanta Falcons at Arizona Cardinals | |||
 27 | Cardinals QB Kurt Warner passed for three touchdowns last week and could have success against a Falcons defense that gave up several big plays. Falcons RB Jerious Norwood should have success against a Cardinals defense that allowed Aaron Stecker to rush for 95 yards. Result: Arizona Cardinals 30, Atlanta Falcons 27 | ||
 19 | |||
| Tampa Bay Buccaneers at San Francisco 49ers | |||
 20 | The Buccaneers have averaged 121 rushing yards per game this season, but could struggle against a 49ers defense that held Rudi Johnson to 16 yards on seven carries. 49ers QB Shaun Hill will test a Buccaneers defense that held Chris Redman to 34 passing yards with two interceptions. Result: Tampa Bay Buccaneers 19, San Francisco 49ers 21 | ||
 14 | |||
| NY Jets Jets at Tennessee Titans | |||
 24 | Titans QB Vince Young passed for 191 yards with two touchdowns last week. Young could struggle against a Jets defense that limited Tom Brady to a season-low 140 yards passing. Jets RB Thomas Jones could have success against a Titans defense that allowed Kolby Smith to gain 82 yards on 18 carries. Result: Tennessee Titans 10, NY Jets Jets 6 | ||
 17 | |||
| Miami Dolphins at New England Patriots | |||
 35 | Last week, Patriots QB Tom Brady passed for a season-low 140 yards and no touchdowns. Brady hopes to rebound this week against a Dolphins defense that recorded four sacks against the Ravens. Dolphins QB Cleo Lemon could struggle against a tough Patriots defense. Result: New England Patriots 28, Miami Dolphins 7 | ||
 13 | |||
| Baltimore Ravens at Seattle Seahawks | |||
 26 | Seahawks QB Matt Hasselbeck passed for 274 yards and a touchdown last week and should have similar success against a Ravens defense that gave up 315 passing yards against the Dolphins. Ravens RB Willis McGahee will test a Seahawks defense that kept Carolina in check until DeAngelo Williams broke off a 35-yard touchdown. Result: Seattle Seahawks 27, Baltimore Ravens 6 | ||
 16 | |||
| Washington Redskins at Minnesota Vikings | |||
 26 | Vikings RB Adrian Peterson, who rushed for 78 yards with two touchdowns last week, faces a Redskins defense that allowed 139 yards on 28 carries. Redskins QB Todd Collins could struggle against a Vikings defense that held Chicago to 177 net yards. Result: Minnesota Vikings 21, Washington Redskins 32 | ||
 17 | |||
| Monday, Dec. 24, 2007 | |||
| Denver Broncos at San Diego Chargers | |||
 29 | Chargers RB LaDainian Tomlinson rushed for 116 yards with two touchdowns last week. Tomlinson should have similar success against a Bronocs defense that gave up 158 rushing yards to rookie RB Darius Walker. Broncos QB Jay Cutler could struggle against a Chargers defense that intercepted five passes last week. Result: San Diego Chargers 23, Denver Broncos 3 | ||
 19 | |||
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