| Date | Player | Pos. | Transaction |
| 5/2 | Josh Willingham | LF | Placed on 15-Day DL, (Lower back soreness) |
| 5/2 | Brett Carroll | RF | Called Up from Minors |
| 5/1 | Steve Woodard | | Signed to a Minor League Contract |
| 4/18 | Lee Gardner | P | Placed on 15-Day DL, (Right elbow inflammation) |
| 4/18 | Doug Waechter | P | Purchased From Minors |
| 4/18 | Sergio Mitre | P | Transferred to 60-Day DL, (Strained right forearm - out 4-6 weeks) |
| 4/11 | Mike Rabelo | C | Removed From 15-Day DL, (Left knee sprain) |
| 4/11 | Paul Hoover | C | Sent to Minors |
| 4/11 | Mike Rabelo | C | Recalled From Minors, Rehab Assignment |
| 4/9 | Jason Wood | 1B | Outrighted to Minors |
| 4/8 | Jeremy Hermida | RF | Recalled From Minors, Rehab Assignment |
| 4/8 | Brett Carroll | RF | Sent to Minors |
| 4/8 | Jeremy Hermida | RF | Removed From 15-Day DL, (Left hamstring tightness) |
| 4/7 | Harvey Garcia | P | Transferred to 60-Day DL, (Right shoulder tendinitis) |
| 4/6 | Rick VandenHurk | P | Sent to Minors |
| 4/5 | Jason Wood | 1B | Designated for Assignment |
| 4/5 | Wes Helms | 3B | Traded From, Philadelphia (for cash and player to be named) |
| 4/3 | Mike Rabelo | C | Sent to Minors, For Rehabilitation |
| 4/3 | Jeremy Hermida | RF | Sent to Minors, For Rehabilitation |
| 3/30 | Alejandro De Aza | CF | Placed on 15-Day DL, (Sprained left ankle) |
| 3/30 | Robert Andino | SS | Called Up from Minors |
| 3/27 | Jorge Cantu | 1B | Purchased From Minors |
| 3/25 | Dallas McPherson | 3B | Sent to Minors |
| 3/24 | Robert Andino | SS | Sent to Minors |
| 3/24 | Anibal Sanchez | P | Placed on 15-Day DL, (Recovery from right shoulder surgery) |
| 3/24 | Henry Owens | P | Placed on 15-Day DL, (Recovery from right shoulder surgery) |
| 3/24 | Sergio Mitre | P | Placed on 15-Day DL, (Strained right forearm - out 4-6 weeks) |
| 3/24 | Cameron Maybin | LF | Sent to Minors |
| 3/24 | Josh Johnson | P | Placed on 15-Day DL, (Recovery from right elbow surgery) |
| 3/24 | Harvey Garcia | P | Placed on 15-Day DL, (Right shoulder tendinitis) |
| 3/20 | Brett Carroll | CF | Sent to Minors |
| 3/14 | Ross Wolf | P | Sent to Minors |
| 3/12 | Daniel Barone | P | Sent to Minors |
| 3/10 | Eulogio De La Cruz | P | Sent to Minors |
| 3/9 | Jorge Piedra | LF | Released |
| 2/13 | Marcos Carvajal | P | Outrighted to Minors |
| 2/8 | Chris Seddon | P | Outrighted to Minors |
| 2/7 | Luis Gonzalez | LF | Signed as Free Agent, ( 2008) |
| 2/7 | Marcos Carvajal | P | Designated for Assignment |
| 1/31 | Chris Seddon | P | Designated for Assignment |
| 1/31 | Dallas McPherson | 3B | Signed as Free Agent, ( 2008) |
| 1/31 | Luis Gonzalez | LF | Signed as Free Agent, ( 2008) |
| 1/18 | Alfredo Amezaga | CF | Signed, ( 2008)(avoids arbitration) |
| 1/18 | Sergio Mitre | P | Signed, ( 2008)(avoids arbitration) |
| 1/18 | Kevin Gregg | P | Signed, ( 2008)(avoids arbitration) |
| 1/17 | Matt Treanor | C | Signed, ( 2008)(avoids arbitration) |
| 1/16 | Randy Williams | | Signed to a Minor League Contract |
| 1/16 | Mark Hendrickson | P | Signed as Free Agent, ( 2008) |
| 1/4 | Bobby Keppel | P | Signed to a Minor League Contract |
| 1/4 | Marc Gwyn | P | Signed to a Minor League Contract |
| 1/4 | Alexis Gomez | RF | Signed to a Minor League Contract |
| 1/4 | Tim Corcoran | P | Signed to a Minor League Contract |
| 1/4 | Jorge Cantu | 1B | Signed to a Minor League Contract |
| 1/4 | Chris Barnwell | SS | Signed to a Minor League Contract |
| 1/4 | Joe Nelson | P | Signed to a Minor League Contract |
| 1/4 | Jorge Piedra | LF | Signed to a Minor League Contract |
| 1/4 | Doug Waechter | P | Signed to a Minor League Contract |
| 1/4 | Jason Wood | 1B | Signed to a Minor League Contract |
| 12/24 | Jose Castillo | 3B | Signed as Free Agent, ( 2008) |
| 12/13 | Justin Miller | P | Signed, ( 2008)(avoids arbitration) |
| 12/12 | Miguel Olivo | C | Not Offered Contract and Became Free Agent, (non-tendered) |
| 12/4 | Mike Rabelo | C | Traded From, Detroit (for 3B Miguel Cabrera, eight-player deal) |
| 12/4 | Andrew Miller | P | Traded From, Detroit (for 3B Miguel Cabrera, eight-player deal) |
| 12/4 | Eulogio De La Cruz | P | Traded From, Detroit (for 3B Miguel Cabrera, eight-player deal) |
| 12/4 | Cameron Maybin | LF | Traded From, Detroit (for 3B Miguel Cabrera, eight-player deal) |
| 11/12 | Josh Johnson | P | Removed From 60-Day DL, (Right forearm stiffness) |
| 11/12 | Henry Owens | P | Removed From 60-Day DL, (Right shoulder surgery - out for season) |
| More Transactions |
| Posted Sun May 04 22:09:47 EDT 2008 |
